Genetic polymorphism among six Trypanosoma cruzi stocks isolated from chronic chagasic patients.
نویسندگان
چکیده
Laboratório Dra. Maria do Carmo Moreira de Souza, Departamento de Parasitologia, Instituto de Patologia Tropical e Saúde Pública, Rua Delenda Rezende de Melo, s/no, Setor Universitário, 74605-050 Goiânia, GO, Brasil *Laboratório de Biologia Molecular, Instituto de Ciências Biologicas **Laboratório de Pesquisa da Doença de Chagas, Hospital das Clínicas, Universidade Federal de Goiás, Goiânia, GO, Brasil
منابع مشابه
Trypanosoma cruzi isolates from Mexican and Guatemalan acute and chronic chagasic cardiopathy patients belong to Trypanosoma cruzi I.
Trypanosoma cruzi is classified into two major groups named T. cruzi I and T. cruzi II. In the present work we analyzed 16 stocks isolated from human cases and four isolated from triatomines from diverse geographical origins (Mexico and Guatemala). From human cases four were acute cases, six indeterminates, and six from chronic chagasic cardiophatic patients with diagnosis of dilated cardiomyop...
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TNF-alpha plays an important role in trypanocidal mechanisms and is related to tissue injury. This cytokine has been detected in the heart of human chagasic patients where it is associated with tissue damage. This study investigated whether TNF-alpha levels and the presence of genetic polymorphisms are associated with the presence of T. cruzi infection and/or with the development of the cardiac...
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ورودعنوان ژورنال:
- Memorias do Instituto Oswaldo Cruz
دوره 94 5 شماره
صفحات -
تاریخ انتشار 1999